Synology DiskStation DS1621xs+ — RAM, Storage & Compatibility Guide

The Synology DiskStation DS1621xs+ is a 6-bay NAS designed for enterprise use. It comes with 8GB DDR4 ECC of RAM and can be upgraded to 32GB DDR4 ECC. Powered by the Intel Xeon Quad-Core processor, it offers reliable network-attached storage for file sharing, backups, and media streaming.

This guide covers complete RAM and storage compatibility for the Synology DiskStation DS1621xs+, including upgrade options, maximum supported configurations, and recommended drives.

Specifications Overview

SpecificationDetails
NAS ModelSynology DiskStation DS1621xs+
BrandSynology
Drive Bays6 bays
ProcessorIntel Xeon Quad-Core
Default RAM8GB DDR4 ECC
Maximum RAM32GB DDR4 ECC
RAM TypeDDR4 ECC
RAM Slots2
RAM UpgradeableYes
M.2 Slots2 (2280 NVMe)
Ethernet4x 1GbE + 1x 10GbE
USB Ports3x USB 3.2 Gen 1 + 2x eSATA
Use CaseEnterprise
Price TierHigh-End

Memory (RAM) Compatibility

The Synology DiskStation DS1621xs+ ships with 8GB DDR4 ECC and supports a maximum of 32GB DDR4 ECC across 2 slots. Upgrading your NAS RAM can significantly improve performance for virtual machines, Docker containers, and simultaneous user access.

Recommended RAM Upgrades

ModuleCapacityPrice
Crucial ECC SODIMM4GBCheck Price
Crucial ECC SODIMM8GBCheck Price
Crucial ECC SODIMM16GBCheck Price

Storage Compatibility

NVMe SSD installed on circuit board
NVMe SSD installed on circuit board

The Synology DiskStation DS1621xs+ has 6 drive bays supporting 3.5″ SATA HDDs and 2.5″ SATA SSDs.

It also includes 2 M.2 slots (2280 NVMe) for NVMe SSD caching, which can dramatically improve random read/write performance.

Recommended NAS Hard Drives

DriveCapacityPrice
Seagate IronWolf4TBCheck Price
Seagate IronWolf8TBCheck Price
WD Red Plus4TBCheck Price
WD Red Plus8TBCheck Price

Recommended NVMe Cache Drives

DriveCapacityPrice
WD Red SN700500GB NVMeCheck Price
Seagate IronWolf 525500GB NVMeCheck Price

Network Connectivity

The Synology DiskStation DS1621xs+ features 4x 1GbE + 1x 10GbE Ethernet and 3x USB 3.2 Gen 1 + 2x eSATA connectivity.

With high-speed Ethernet, this NAS can fully utilise fast NVMe cache drives and multiple concurrent connections.

Related Guides

Frequently Asked Questions

What is the maximum RAM for the Synology DiskStation DS1621xs+?

The Synology DiskStation DS1621xs+ supports a maximum of 32GB DDR4 ECC. It ships with 8GB DDR4 ECC by default.

How many drive bays does the Synology DiskStation DS1621xs+ have?

The Synology DiskStation DS1621xs+ has 6 drive bays supporting 3.5″ SATA HDDs and 2.5″ SATA SSDs. It also has 2 M.2 slots for NVMe SSD caching.

Can I upgrade the RAM in the Synology DiskStation DS1621xs+?

Yes, the RAM is user-upgradeable.

What hard drives work with the Synology DiskStation DS1621xs+?

The Synology DiskStation DS1621xs+ works with standard 3.5″ SATA HDDs. We recommend NAS-rated drives like the Seagate IronWolf or WD Red Plus.

💰 Compare PricesShop around for the best deal on Synology NAS drives
Affiliate disclosure: We may earn a commission from purchases made through these links at no extra cost to you.

Shop Compatible Upgrades at PCHub.UK

Prices updated automatically from PCHub.UK — click to view full specs and buy

Hypertec HYMAC9601G (Legacy) memory module 1 GB DDR2 200-pin SO-DIMM
RAM 1GB

Hypertec HYMAC9601G (Legacy) memory module 1 GB DDR2 200-pin SO-DIMM

£13.70 View Deal
Hypertec HYS31025684GB memory module 4 GB DDR3 204-pin SO-DIMM
RAM 31025.7TB

Hypertec HYS31025684GB memory module 4 GB DDR3 204-pin SO-DIMM

£14.76 View Deal
2-Power 2P-4X71M23184 memory module 8 GB 1 x 8 GB DDR5 262-pin SO-DIMM
DDR5 8GB

2-Power 2P-4X71M23184 memory module 8 GB 1 x 8 GB...

£125.20 View Deal
2-Power 8GB DDR5 5600MHz CL40 SoDIMM
DDR5 8GB

2-Power 8GB DDR5 5600MHz CL40 SoDIMM

Speed: 5600 MHz

£125.20 View Deal
Kingston Technology 7mm to 9.5mm 2.5in SSD adapter
NVMe

Kingston Technology 7mm to 9.5mm 2.5in SSD adapter

£14.06 View Deal
StarTech.com 3.5in Drive Bay IDE to Single CF SSD Adapter Card Reader
NVMe

StarTech.com 3.5in Drive Bay IDE to Single CF SSD Adapter...

£26.84 View Deal

Prices from PCHub.UK via ComputersDeal. As an affiliate, we may earn from qualifying purchases. Prices updated 2026-04-10 13:15:58.

Leave a Comment

Your email address will not be published. Required fields are marked *