The HP ProLiant DL380 Gen10 (2019-2022) is a enterprise server with extensive upgrade potential. This guide covers RAM, storage, and compatibility details. For more HP server guides, visit our HP Servers category.
HP ProLiant DL380 Gen10 Specifications
| Component | Specification |
|---|---|
| Processor | Dual Intel Xeon Scalable 2nd Gen (Cascade Lake) |
| Chipset | Intel C621 |
| RAM Type | DDR4-2933 ECC RDIMM/LRDIMM |
| RAM Slots | 24 DIMM slots (12 per CPU) |
| Max RAM | 3TB (24x 128GB LRDIMM) |
| Storage | 24x 2.5″ or 12x 3.5″ hot-plug SAS/SATA/NVMe |
| Form Factor | 2U Rack |
| Release Year | 2019-2022 |
HP ProLiant DL380 Gen10 RAM Upgrade Guide
The HP ProLiant DL380 Gen10 supports DDR4-2933 ECC RDIMM/LRDIMM across 24 DIMM slots (12 per CPU), for a maximum of 3TB (24x 128GB LRDIMM). This system requires ECC (Error-Correcting Code) memory for data integrity in mission-critical workloads.
Compatible RAM
- Kingston Server Premier ECC — Enterprise-grade ECC memory with proven server compatibility.
- Samsung ECC RDIMM — OEM-quality registered ECC modules used in data centres worldwide.
- Crucial ECC UDIMM/RDIMM — Reliable ECC memory with excellent compatibility across server platforms.
HP ProLiant DL380 Gen10 Storage Upgrade Guide
The HP ProLiant DL380 Gen10 supports 24x 2.5″ or 12x 3.5″ hot-plug SAS/SATA/NVMe. Best-selling 2U rack server. Smart Array P408i. Up to 3 PCIe GPU slots.
Recommended Storage
- Samsung 990 Pro NVMe — Flagship NVMe with exceptional speed and endurance for workstation use.
- WD Red Pro / WD Black SN850X — High-reliability drives suited for server and workstation environments.
- Samsung 870 EVO SATA SSD — Reliable SATA SSD with excellent endurance for server boot drives.
- Seagate IronWolf / WD Red Plus — NAS-grade HDDs rated for 24/7 operation in server environments.
Upgrade Notes
The HP ProLiant DL380 Gen10 is designed for easy serviceability. RAM and storage upgrades are tool-free or require only a standard Philips screwdriver. Always ensure the system is powered off and unplugged before performing upgrades. For ECC memory configurations, ensure all modules are matched in speed and capacity for optimal performance.
Frequently Asked Questions
What type of RAM does the HP ProLiant DL380 Gen10 use?
The HP ProLiant DL380 Gen10 uses DDR4-2933 ECC RDIMM/LRDIMM across 24 DIMM slots (12 per CPU), supporting up to 3TB (24x 128GB LRDIMM).
Can I mix RAM sizes in the HP ProLiant DL380 Gen10?
While technically possible, mixing RAM sizes is not recommended for servers. Use matched pairs or sets for optimal performance and stability.
What storage options does the HP ProLiant DL380 Gen10 support?
The HP ProLiant DL380 Gen10 supports 24x 2.5″ or 12x 3.5″ hot-plug SAS/SATA/NVMe.
Is ECC RAM required for the HP ProLiant DL380 Gen10?
Yes, the HP ProLiant DL380 Gen10 requires ECC memory for reliable operation. Non-ECC modules will not be recognised.
Recommended Products
All links go to Amazon UK where you can check current prices and availability.
| Product | Why We Recommend It | Amazon UK |
|---|---|---|
| Kingston Server Premier ECC | Enterprise-grade ECC memory. | View on Amazon UK |
| Samsung ECC RDIMM | OEM-quality registered modules. | View on Amazon UK |
| Crucial ECC Memory | Reliable ECC with wide compatibility. | View on Amazon UK |
| Samsung 990 Pro NVMe | Flagship NVMe for workstation use. | View on Amazon UK |
| Samsung 870 EVO SATA SSD | Reliable SATA SSD for boot drives. | View on Amazon UK |
Prices and availability may vary. As an Amazon Associate, we earn from qualifying purchases.

