This guide covers everything you need to know about upgrading the RAM and storage on the HP ProLiant DL385 Gen10 Plus (2020). Whether you want faster performance, more memory, or additional storage space, we have the compatibility details and recommended upgrades below.
HP ProLiant DL385 Gen10 Plus — Quick Specs

| Specification | Details |
|---|---|
| Model | HP ProLiant DL385 Gen10 Plus |
| Year | 2020 |
| Type | Server |
| Processor | AMD EPYC 7003 (Milan) |
| RAM Type | DDR4 ECC RDIMM/LRDIMM |
| RAM Form Factor | RDIMM |
| Max RAM | 4096GBGB |
| RAM Slots | 32 DIMM slots |
| Storage Type | NVMe/SATA SSD |
| Storage Slots | Up to 24x 2.5-inch bays |
HP ProLiant DL385 Gen10 Plus Memory (RAM) Upgrade
The HP ProLiant DL385 Gen10 Plus supports DDR4 ECC RDIMM/LRDIMM RDIMM memory modules with a maximum capacity of 4096GBGB. It has 32 DIMM slots.
Recommended RAM Upgrades
| Recommended RAM | Buy |
|---|---|
| Samsung DDR4 ECC RDIMM 32GB 3200MHz | Check Price |
| Kingston Server Premier DDR4 32GB 2666MHz ECC | Check Price |
| Samsung DDR4 ECC RDIMM 16GB 2666MHz | Check Price |
| Micron DDR4 LRDIMM 64GB 2933MHz | Check Price |
HP ProLiant DL385 Gen10 Plus Storage (SSD/HDD) Upgrade
The HP ProLiant DL385 Gen10 Plus supports NVMe/SATA SSD storage with Up to 24x 2.5-inch bays.
Recommended SSD Upgrades
| Recommended SSD | Buy |
|---|---|
| Samsung 970 EVO Plus 1TB NVMe M.2 | Check Price |
| WD Black SN770 1TB NVMe M.2 | Check Price |
| Crucial P3 Plus 500GB NVMe M.2 | Check Price |
| Samsung 870 EVO 1TB 2.5" SATA | Check Price |
| Crucial MX500 500GB 2.5" SATA | Check Price |
Upgrade Difficulty
The HP ProLiant DL385 Gen10 Plus has an upgrade difficulty rating of Moderate. Most users can upgrade the RAM and SSD with basic tools (Phillips screwdriver). Always disconnect the battery before performing any internal upgrades.
Upgrade Tips for the HP ProLiant DL385 Gen10 Plus
- Back up all data before replacing or adding storage drives.
- Use an anti-static wrist strap to prevent damage to components.
- Match RAM speed and type (DDR4 ECC RDIMM/LRDIMM RDIMM) for best compatibility.
- Check your current configuration in the BIOS before ordering parts.
- Consider cloning your existing drive to a new SSD for a seamless transition.
Related Guides
Frequently Asked Questions
What is the maximum RAM for the HP ProLiant DL385 Gen10 Plus?
The HP ProLiant DL385 Gen10 Plus supports a maximum of 4096GBGB of DDR4 ECC RDIMM/LRDIMM RDIMM memory across 32 DIMM slots.
What type of SSD does the HP ProLiant DL385 Gen10 Plus use?
The HP ProLiant DL385 Gen10 Plus uses NVMe/SATA SSD storage with Up to 24x 2.5-inch bays.
Can I upgrade the RAM in the HP ProLiant DL385 Gen10 Plus?
Yes, the HP ProLiant DL385 Gen10 Plus has 32 DIMM slots supporting DDR4 ECC RDIMM/LRDIMM RDIMM modules up to 4096GBGB total.
Is the HP ProLiant DL385 Gen10 Plus worth upgrading?
Upgrading the RAM and SSD in the HP ProLiant DL385 Gen10 Plus can significantly improve performance, especially if you are running out of memory or storage space.
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