The ThinkCentre M75q Gen 2 is a AMD Ryzen Pro 5000 business desktop released in 2021. This guide covers RAM compatibility (DDR4-3200 SO-DIMM), SSD upgrade options including NVMe, and recommended components for maximum performance.
Available in SFF (Small Form Factor) and Tower variants, the ThinkCentre M75q Gen 2 supports up to 64GB of DDR4-3200 SO-DIMM RAM in the Tower configuration and 64GB in the SFF.
ThinkCentre M75q Gen 2 Quick Specifications
| Specification | SFF | Tower |
|---|---|---|
| Processor | AMD Ryzen Pro 5000 | |
| RAM Type | DDR4-3200 SO-DIMM | |
| RAM Slots | 2 | 2 |
| Max RAM | 64GB | 64GB |
| Storage | M.2 NVMe PCIe 3.0 | |
| NVMe Support | Yes | |
| PCIe Generation | 3.0 | |
ThinkCentre M75q Gen 2 RAM Upgrade Guide
Compatible RAM Specifications
The ThinkCentre M75q Gen 2 requires DDR4-3200 SO-DIMM unbuffered DIMMs (UDIMMs). Use non-ECC desktop DIMMs for standard configurations.
Recommended RAM Configurations
| Configuration | Form Factor | Total RAM | Modules |
|---|---|---|---|
| Budget | SFF/Tower | 16GB | 2 × 8GB |
| Standard | SFF | 32GB | 2 × 16GB |
| Standard | Tower | 32GB | 2 × 16GB |
| Maximum (Tower) | Tower | 64GB | 4 × 16GB |
RAM Installation Steps
- Shut down the computer and disconnect all cables including the power cord
- Press the power button for 5 seconds to discharge residual electricity
- Remove the side panel (SFF: slide release latch; Tower: remove thumbscrews)
- Locate the DIMM slots on the motherboard
- Open the retention clips on both sides of the slot
- Align the notch on the RAM module with the key in the slot
- Press down firmly and evenly until the retention clips snap into place
- Replace the side panel and reconnect cables
- Power on and verify RAM is recognised in BIOS (press F10 during startup)
ThinkCentre M75q Gen 2 SSD Upgrade Guide
The ThinkCentre M75q Gen 2 supports M.2 NVMe drives via PCIe 3.0 as well as standard 2.5″ SATA SSDs. NVMe drives offer significantly faster read/write speeds compared to SATA.
M.2 NVMe Installation
- Power off and open the chassis as described above
- Locate the M.2 slot on the motherboard (typically near the CPU or front panel connectors)
- Remove the M.2 mounting screw
- Insert the M.2 drive at a 30-degree angle into the slot
- Press down and secure with the mounting screw
- Reassemble and boot — the drive should appear in BIOS automatically
Recommended Upgrade Products
| Product | Type | Best For | Link |
|---|---|---|---|
| Crucial 16GB DDR4-3200 UDIMM | RAM | 16GB stick | Shop |
| Kingston Fury Beast 16GB DDR4-3200 | RAM | 16GB stick | Shop |
| Corsair Vengeance LPX 32GB DDR4-3200 Kit | RAM | 32GB kit (2×16GB) | Shop |
| Samsung 970 EVO Plus 1TB NVMe | SSD | High performance | Shop |
| WD Blue SN570 1TB NVMe | SSD | Great value | Shop |
| Crucial P3 Plus 1TB NVMe | SSD | Budget NVMe | Shop |
| Samsung 870 EVO 1TB SATA | SSD | SATA upgrade | Shop |
| Crucial MX500 1TB SATA | SSD | Budget SATA | Shop |
Prices and availability may vary. As an Amazon Associate, we earn from qualifying purchases.
Frequently Asked Questions
Q: What type of RAM does the ThinkCentre M75q Gen 2 use?
A: The ThinkCentre M75q Gen 2 uses DDR4-3200 SO-DIMM unbuffered DIMMs (UDIMMs). The SFF model has 2 DIMM slots supporting up to 64GB, while the Tower model has 2 slots supporting up to 64GB.
Q: Can I add an NVMe SSD to the ThinkCentre M75q Gen 2?
A: Yes, the ThinkCentre M75q Gen 2 supports M.2 NVMe drives via PCIe 3.0. This is the recommended upgrade for maximum storage performance.
Q: Is the ThinkCentre M75q Gen 2 RAM compatible with the ThinkCentre M75q Gen series?
A: RAM compatibility depends on the specific generation. The ThinkCentre M75q Gen 2 uses DDR4-3200 SO-DIMM, which is physically compatible with other DDR4 systems but the speed rating must match or exceed the motherboard’s requirement.
Q: How do I check how much RAM is currently installed?
A: Open Task Manager (Ctrl+Shift+Esc), click the Performance tab, then select Memory. This shows total installed RAM, speed, form factor, and how many slots are in use. Alternatively, press Win+Pause/Break to open System Information.
Q: Can I mix different RAM sizes in the ThinkCentre M75q Gen 2?
A: While the ThinkCentre M75q Gen 2 can technically run with mismatched RAM sizes, it is recommended to use identical modules in pairs for optimal dual-channel performance. Mixing sizes will cause the system to run in flex mode, which reduces memory bandwidth.

