The Synology DS1621xs+ is a 6-bay NAS from Synology in the DiskStation range. It comes with 8GB of DDR4 ECC SO-DIMM RAM (upgradeable to 32GB) and supports 3.5-inch SATA HDD/SSD + 2x M.2 NVMe drives. This guide covers compatible RAM and storage upgrades with our top recommendations.
Synology DS1621xs+ Specifications
| NAS Model | Synology DS1621xs+ |
| Brand | Synology |
| Series | DiskStation |
| Drive Bays | 6 |
| Processor | Intel Xeon D-1527 |
| Default RAM | 8GB |
| Max RAM | 32GB |
| RAM Type | DDR4 ECC SO-DIMM |
| RAM Slots | 2 |
| Drive Compatibility | 3.5-inch SATA HDD/SSD + 2x M.2 NVMe |
| Network | 2x 10GbE + 1x 1GbE |
| Release Year | 2020 |
Compatible RAM for Synology DS1621xs+
The Synology DS1621xs+ ships with 8GB and can be upgraded to a maximum of 32GB. It uses DDR4 ECC SO-DIMM SO-DIMM modules (2 slots).
Recommended RAM Upgrades
| Capacity | Module | Buy |
|---|---|---|
| 4GB | Crucial DDR4-2666 4GB SO-DIMM | Check Price |
| 8GB | Crucial DDR4-2666 8GB SO-DIMM | Check Price |
| 16GB | Crucial DDR4-2666 16GB SO-DIMM | Check Price |
Compatible Storage Drives
The Synology DS1621xs+ has 6 drive bays supporting 3.5-inch SATA HDD/SSD + 2x M.2 NVMe. Here are our top drive recommendations:
Recommended NAS Drives
| Capacity | Drive | Buy |
|---|---|---|
| 4TB HDD | Seagate IronWolf 4TB NAS HDD | Check Price |
| 8TB HDD | Seagate IronWolf 8TB NAS HDD | Check Price |
| 16TB HDD | Seagate IronWolf Pro 16TB NAS HDD | Check Price |
| 1TB NVMe | Samsung 970 EVO Plus 1TB M.2 NVMe | Check Price |
Setup Tips
- Use NAS-rated drives: Always use drives designed for NAS use (e.g. Seagate IronWolf, WD Red Plus) for reliability and vibration resistance.
- RAID configuration: For data protection, use RAID 1 (mirroring) for 2-bay units or RAID 5/SHR for 4+ bay units.
- RAM upgrade: Upgrading RAM improves multitasking, virtualisation and app performance. Use Synology-compatible modules.
- Network: Connect via Ethernet for best performance. This model supports 2x 10GbE + 1x 1GbE.
Frequently Asked Questions
What is the maximum RAM for the Synology DS1621xs+?
The Synology DS1621xs+ supports up to 32GB of DDR4 ECC SO-DIMM RAM.
How many drive bays does the Synology DS1621xs+ have?
The Synology DS1621xs+ has 6 drive bays supporting 3.5-inch SATA HDD/SSD + 2x M.2 NVMe.
What drives are compatible with the Synology DS1621xs+?
The Synology DS1621xs+ supports 3.5-inch SATA HDD/SSD + 2x M.2 NVMe. We recommend NAS-rated drives like the Seagate IronWolf or WD Red Plus series.

