Synology RS2421+ RAM & Storage Compatibility

The Synology RS2421+ is a 12-bay NAS from Synology in the RackStation range. It comes with 4GB of DDR4 ECC SO-DIMM RAM (upgradeable to 32GB) and supports 4x 1GbE drives. This guide covers compatible RAM and storage upgrades with our top recommendations.

Synology RS2421+ Specifications

Internal hard disk drives for NAS storage
Internal hard disk drives for NAS storage
NAS ModelSynology RS2421+
BrandSynology
SeriesRackStation
Drive Bays12
ProcessorAMD Ryzen V1500B
Default RAM4GB
Max RAM32GB
RAM TypeDDR4 ECC SO-DIMM
RAM Slots2
Drive Compatibility4x 1GbE
Network3.5-inch SATA HDD/SSD
Release Year2020

Compatible RAM for Synology RS2421+

The Synology RS2421+ ships with 4GB and can be upgraded to a maximum of 32GB. It uses DDR4 ECC SO-DIMM SO-DIMM modules (2 slots).

Recommended RAM Upgrades

CapacityModuleBuy
4GBCrucial DDR4-2666 4GB SO-DIMMCheck Price
8GBCrucial DDR4-2666 8GB SO-DIMMCheck Price
16GBCrucial DDR4-2666 16GB SO-DIMMCheck Price

Compatible Storage Drives

The Synology RS2421+ has 12 drive bays supporting 4x 1GbE. Here are our top drive recommendations:

Recommended NAS Drives

CapacityDriveBuy
4TB HDDSeagate IronWolf 4TB NAS HDDCheck Price
8TB HDDSeagate IronWolf 8TB NAS HDDCheck Price
16TB HDDSeagate IronWolf Pro 16TB NAS HDDCheck Price

Setup Tips

  • Use NAS-rated drives: Always use drives designed for NAS use (e.g. Seagate IronWolf, WD Red Plus) for reliability and vibration resistance.
  • RAID configuration: For data protection, use RAID 1 (mirroring) for 2-bay units or RAID 5/SHR for 4+ bay units.
  • RAM upgrade: Upgrading RAM improves multitasking, virtualisation and app performance. Use Synology-compatible modules.
  • Network: Connect via Ethernet for best performance. This model supports 3.5-inch SATA HDD/SSD.

Frequently Asked Questions

What is the maximum RAM for the Synology RS2421+?

The Synology RS2421+ supports up to 32GB of DDR4 ECC SO-DIMM RAM.

How many drive bays does the Synology RS2421+ have?

The Synology RS2421+ has 12 drive bays supporting 4x 1GbE.

What drives are compatible with the Synology RS2421+?

The Synology RS2421+ supports 4x 1GbE. We recommend NAS-rated drives like the Seagate IronWolf or WD Red Plus series.

Related Synology Upgrade Guides

Not sure what fits? Use our free Compatibility Checker covering 3,195+ models.

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Shop Compatible Upgrades at PCHub.UK

Prices updated automatically from PCHub.UK — click to view full specs and buy

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Prices from PCHub.UK via ComputersDeal. As an affiliate, we may earn from qualifying purchases. Prices updated 2026-04-10 13:15:58.

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